Articles

O.6 Multipotent mesenchymal stromal cells for poor graft function after allogeneic hematopoietic cell transplantation – a multicenter prospective study

BJH - volume 11, issue Abstract Book BHS, february 2020

S. Servais MD, PhD, F. Baron MD, PhD, C. Lechanteur PhD, E. Baudoux MD, A. Briquet PhD, D. Selleslag MD, J. Maertens MD, PhD, X. Poiré MD, W. Schroyens MD, PhD, C. Graux MD, PhD, A. De Becker MD, R. Schots MD, PhD, P. Zachée MD, PhD, A. Ory , J. Herman , T. Kerre MD, PhD, Y. Beguin MD, PhD

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Multipotent mesenchymal stromal cell therapy for steroid-refractory acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation

BJH - volume 7, issue 6, december 2016

S. Servais MD, PhD, C. Grégoire MD, F. Baron MD, PhD, E. Willems MD, PhD, A. Briquet PhD, E. Baudoux MD, O. Delloye PhD, O. Giet PhD, C. Lechanteur PhD, Y. Beguin MD, PhD

Summary

Steroid-refractory acute graft-versus-host disease is a severe complication after allogeneic stem cell transplantation. So far, its treatment remains very challenging since the current therapies do not offer significant benefits. Among the most recent approaches, multipotent mesenchymal stromal cell-based therapy has attracted great interest over the past decade. Here, we briefly reviewed the current knowledges about the immunomodulatory properties of multipotent mesenchymal stromal cells as well as results of preclinical and clinical studies having assessed their efficacy to modulate steroid-refractory acute graft-versus-host disease.

(BELG J HEMATOL 2016;7(6):229–35)

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PP3.2 Umbilical cord mesenchymal stromal cells are superior to bone marrow and adipose tissue-derived mesenchymal stromal cells for the treatment of xenogeneic graft-versus-host disease in mice

BJH - volume 7, issue Abstract Book BHS, january 2016

C. Grégoire MD, Y. Beguin MD, PhD, M. Hannon , S. Dubois , B. Baudoux , A. Briquet PhD, C. Lechanteur PhD, G. Ehx , F. Baron MD, PhD

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O.2 Establishment of a murine graft-versus-myeloma model using allogeneic stem cell transplantation

BJH - volume 5, issue Abstract Book BHS, january 2014

M. Binsfeld , Y. Beguin MD, PhD, L. Belle , E. Otjacques , M. Hannon , A. Briquet PhD, P. Drion , B. Bogen , F. Baron MD, PhD, J. Caers MD, PhD

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O.4 Combination of regulatory T cells injection with rapamycin for treatment of chronic Graft-versus-Host disease

BJH - 2013, issue BHS Abstractbook, january 2013

L. Belle , M. Binsfeld , M. Hannon , J. Caers MD, PhD, A. Briquet PhD, M. Menten , Y. Beguin MD, PhD, S. Humblet , F. Baron MD, PhD

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P.52 Neuropeptides to replace serum in cryopreservation of mesenchymal stem cells?

BJH - 2013, issue BHS Abstractbook, january 2013

A. Briquet PhD, A. Halleux , C. Lechanteur PhD, Y. Beguin MD, PhD

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