Articles

O.4 An in-depth investigation of the causes of treatment failure in AML

BJH - volume 11, issue Abstract Book BHS, february 2020

S. Bonte , S. Van Gassen , A. Couckuyt , V. Janda , I. Moors MD, A. Delie , S. Kennes , J. Philippé MD, PhD, Y. Saeys , T. Kerre MD, PhD

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Impact of new treatment guidelines pertaining to the indication for allogeneic stem cell transplantation in intermediate-risk acute myeloid leukaemia at Ghent University Hospital: A retrospective analysis

BJH - volume 9, issue 7, december 2018

A. Delie , T. Kerre MD, PhD, I. Moors MD

SUMMARY

Since several years, it has become clear that intermediate-risk acute myeloid leukaemia patients in an acceptable clinical condition can benefit from allogeneic stem cell transplantation thanks to the improvement in relapse free survival. This study retrospectively analysed the outcome of all intermediate-risk acute myeloid leukaemia patients treated with intensive chemotherapy at the Ghent University Hospital between 01-01-2013 and 30-04-2017 in an effort to determine the impact of a new in-hospital treatment guideline adopted in April 2015. This guideline recommends all intermediate-risk acute myeloid leukaemia patients who are fit for intensive therapy to proceed to allogeneic stem cell transplantation in first complete remission. Unfortunately, we could not demonstrate an improvement in the relapse free survival after implementation of the treatment guideline. Nevertheless, exploratory analysis of the entire group suggests a survival benefit from allogeneic stem cell transplantation, with significantly improved relapse free survival and a trend towards a better overall survival.

(BELG J HEMATOL 2018;9(7):285–9)

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P09 A case of chronic eosinophilic leukemia with secondary transformation to acute myeloid leukemia

BJH - 2018, issue Abstract Book BHS, february 2018

M. Hofmans MD, A. Delie , K. Vandepoele PhD, N. Van Roy PhD, J. Van der Meulen , J. Philippé MD, PhD, I. Moors MD

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P45 Donor cell derived deletion 7q occurring after allogeneic stem cell transplantation: a case report

BJH - 2018, issue Abstract Book BHS, february 2018

A. Delie , P. Vlummens MD, N. Van Roy PhD, F. Offner MD, PhD, T. Kerre MD, PhD

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