BJH - volume 11, issue Abstract Book BHS, february 2020
G. Crochet , M. Bourgeois , E. Collinge , H. Vellemans , M. André MD, A. Sonet MD, C. Graux MD, PhD
BJH - volume 6, issue Abstract Book BHS, january 2015
D. Gheldof , J-M. Dogné PhD, PharmD, C. Graux MD, PhD, G. Fabienne , A. Sonet MD, B. Chatelain PharmD, F. Mullier PhD, PharmD, C. Chatelain MD
BJH - volume 5, issue 3, september 2014
E. Mourin MD, A. Van Hoof MD, PhD, A. Bosly MD, PhD, C. Bonnet MD, PhD, V. De Wilde MD, PhD, C. Doyen MD, PhD, C. Hermans MD, PhD, A. Janssens MD, PhD, L. Michaux MD, PhD, W. Schroyens MD, PhD, A. Sonet MD, E. Van den Neste MD, PhD, G. Verhoef MD, PhD, P. Zachée MD, PhD, M. André MD
Mantle cell lymphoma was recognised in the nineties and is characterised by the t(11;14)(q13;q32) translocation which results in overexpression of cyclin D1.1 This disease represents approximately 6% of all non-Hodgkin’s lymphomas. Mantle cell lymphoma generally affects patients over 60 years-old. Most patients have advanced disease (>70 % Ann Arbor stage IV). Several efforts have been made to predict outcome in mantle cell lymphoma. The cell-proliferation marker Ki-67, the Mantle Cell Lymphoma International Prognostic Index, fluorodeoxyglucose positron emission tomography and minimal residual disease are prognostic tools. For young patients, chemoimmunotherapy followed by high-dose chemotherapy plus stem cell transplantation is the treatment of choice. For the main group of older patients, chemo-immunotherapy followed by maintenance with rituximab is the gold standard. In relapses, temsirolimus is actually registered and new drugs, such as ibrutinib, are currently evaluated with promising preliminary results.2–5
(BELG J HEMATOL 2014;5(3):89–96)
Read moreBJH - volume 5, issue Abstract Book BHS, january 2014
M. André MD, B. De Prijck MD, A. Kentos MD, A. Van Hoof MD, PhD, C. Bonnet MD, PhD, A. Sonet MD, M. Maerevoet MD, E. Van den Neste MD, PhD, A. Bosly MD, PhD, N. Mounier
BJH - volume 4, issue 3, september 2013
F. Van Obbergh MD, A. Van Hoof MD, PhD, G. Verhoef MD, PhD, D. Dierickx MD, PhD, V. De Wilde MD, PhD, F. Offner MD, PhD, D. Bron MD, PhD, A. Sonet MD, M. André MD, A. Janssens MD, PhD, C. Bonnet MD, PhD, B. Deprijck MD, P. Zachée MD, PhD, A. Kentos MD, W. Schroyens MD, PhD, E. Van den Neste MD, PhD
The sub-committee on lymphoproliferative disorders of the Belgian Hematological Society has met several times to prepare guidelines on the management of patients with peripheral T-cell lymphomas. Each panellist’s expert provided interpretation of the evidence, based on literature review and personal experience. The available evidence was systematically discussed prior to formulating recommendations. A systematic approach to obtain consensus of expert opinion was used. After each meeting, the draft guideline was circulated to all experts for comment and approval. The present guidelines focus on general management of peripheral T-cell lymphomas with special emphasis on more specific disease-adapted strategies.
(BELG J HEMATOL 2013;4(3):90–101)
Read moreBJH - 2013, issue BHS Abstractbook, january 2013
S. Ludovicy , C. Graux MD, PhD, A. Sonet MD, A. Charpentier , K. Chalabi , L. Plawny MD
BJH - 2013, issue BHS Abstractbook, january 2013
M. Bourgeois , A. Sonet MD, C. Graux MD, PhD, C. Chatelain MD, C. Doyen MD, PhD, C. Baiana , C. Crivisqui , Y. Glupczynski , M. André MD