Articles

PP43 Graft-versus-host disease (GVHD) of the central nervous system (CNS) after allogeneic hematopoietic cell transplantation (alloHCT): case report

BJH - 2018, issue Abstract Book BHS, february 2018

M. Pirotte , F. Forte , L. Lutteri , B. Otto , E. Willems MD, PhD, L. Belle , F. Baron MD, PhD, Y. Beguin MD, PhD, P. Maquet , O. Bodard , S. Servais MD, PhD

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Multipotent mesenchymal stromal cell therapy for steroid-refractory acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation

BJH - volume 7, issue 6, december 2016

S. Servais MD, PhD, C. Grégoire MD, F. Baron MD, PhD, E. Willems MD, PhD, A. Briquet PhD, E. Baudoux MD, O. Delloye PhD, O. Giet PhD, C. Lechanteur PhD, Y. Beguin MD, PhD

Summary

Steroid-refractory acute graft-versus-host disease is a severe complication after allogeneic stem cell transplantation. So far, its treatment remains very challenging since the current therapies do not offer significant benefits. Among the most recent approaches, multipotent mesenchymal stromal cell-based therapy has attracted great interest over the past decade. Here, we briefly reviewed the current knowledges about the immunomodulatory properties of multipotent mesenchymal stromal cells as well as results of preclinical and clinical studies having assessed their efficacy to modulate steroid-refractory acute graft-versus-host disease.

(BELG J HEMATOL 2016;7(6):229–35)

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PP2.1 Immunomodulatory effects of rapamycin in Graft versus Host Disease

BJH - volume 7, issue Abstract Book BHS, january 2016

G. Ehx , M. Hannon , S. Humblet-Baron , S. Dubois , C. Daulne , P. Drion , E. Willems MD, PhD, S. Servais MD, PhD, Y. Beguin MD, PhD, F. Baron MD, PhD

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O.4 Impact of pre-transplant infusion of antithymocyte globulin (ATG-Fresenius) on immune recovery after high intensity conditioning allogeneic stem cell transplantation

BJH - volume 6, issue Abstract Book BHS, january 2015

S. Servais MD, PhD, C. Menten , Y. Beguin MD, PhD, C. Daulne , L. Delens , E. Willems MD, PhD, M. Hannon , F. Baron MD, PhD

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P3.03 Study of immune recovery in a randomized phase II trial of sequential double autologous transplantation with unmanipulated or AC133+ PBSC in patients with multiple myeloma

BJH - volume 6, issue Abstract Book BHS, january 2015

M. Hannon , S. Servais MD, PhD, R. Schots MD, PhD, E. Castermans , L. Seidel , A. Gothot MD, PhD, E. Baudoux MD, O. Giet PhD, N. Wanten , E. Willems MD, PhD, C. Daulne , I. Van Riet PhD, Y. Beguin MD, PhD, F. Baron MD, PhD

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P3.05 Long-term safety follow-up of a randomized trial of darbepoetin alpha and intravenous iron following autologous hematopoietic cell transplantation

BJH - volume 6, issue Abstract Book BHS, january 2015

A. Jaspers MD, PhD, F. Baron MD, PhD, J. Maertens MD, PhD, B. De Prijck MD, R. Schots MD, PhD, C. Bonnet MD, PhD, K. Hafraoui , E. Willems MD, PhD, S. Servais MD, PhD, G. Fillet , Y. Beguin MD, PhD

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P3.06 Immune Recovery after Allogeneic Hematopoietic Stem Cell Transplantation following Flu-TBI versus TLI-ATG Conditioning

BJH - volume 6, issue Abstract Book BHS, january 2015

M. Hannon , Y. Beguin MD, PhD, G. Ehx , S. Servais MD, PhD, L. Seidel , C. Graux MD, PhD, J. Maertens MD, PhD, T. Kerre MD, PhD, C. Daulne , M. De Bock , M. Fillet , A. Ory , E. Willems MD, PhD, A. Gothot MD, PhD, S. Humblet-Baron , F. Baron MD, PhD

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