BJH - volume 11, issue Abstract Book BHS, february 2020
E. Linskens , S. Van Landeghem , K. Vandepoele PhD, K. Maes , I. Moors MD, J. Van Dorpe , C. Bonroy , K. Devreese , J. Philippé MD, PhD, B. Denys PharmD
BJH - volume 11, issue Abstract Book BHS, february 2020
S. Bonte , S. Van Gassen , A. Couckuyt , V. Janda , I. Moors MD, A. Delie , S. Kennes , J. Philippé MD, PhD, Y. Saeys , T. Kerre MD, PhD
BJH - 2018, issue Abstract Book BHS, february 2018
M. Hofmans MD, T. Lammens PhD, S. Bresolin , H. Cavé , C. Flotho , H. Hasle , H. Helsmoortel PhD, M. Van den Heuvel-Eibrink , C. Niemeyer , J. Stary , N. Van Roy PhD, P. Van Vlierberghe PhD, J. Philippé MD, PhD, B. De Moerloose MD, PhD
BJH - 2018, issue Abstract Book BHS, february 2018
B. Stamatopoulos , T. Smith , E. Crompot , K. Pieters , R. Clifford , M. Mraz , P. Robbe , A. Burns , A. Timbs , D. Bruce , P. Hillmen , N. Meuleman MD, PhD, P. Mineur MD, R. Firescu , M. Maerevoet MD, V. De Wilde MD, PhD, A. Efira MD, J. Philippé MD, PhD, B. Verhasselt MD, PhD, F. Offner MD, PhD, A. Heger , D. Sims , H. Dreau , A. Schuh
BJH - 2018, issue Abstract Book BHS, february 2018
M. Hofmans MD, A. Delie , K. Vandepoele PhD, N. Van Roy PhD, J. Van der Meulen , J. Philippé MD, PhD, I. Moors MD
BJH - 2018, issue Abstract Book BHS, february 2018
K. Imaeva , P. Vlummens MD, S. Verbeke , J. Philippé MD, PhD, I. Moors MD
BJH - volume 8, issue 2, march 2017
A-S. De Koninck PharmD, C. Dhooge MD, PhD, B. Denys PharmD, K. Vandepoele PhD, N. Van Roy PhD, M. Hofmans MD, J. Philippé MD, PhD
We describe a case of a four-year-old boy diagnosed with an Early T-cell Precursor Lymphoblastic Leukaemia. This type of leukaemia is recognised as a high-risk subgroup characterised by very early arrest in T-cell differentiation. Early T-cell Precursor Lymphoblastic Leukaemia cases have characteristic gene expression profiles, increased genomic instability and a distinct immature immunophenotype (CD1a–, CD8–, CD5+dim and positivity for at least one marker of stem cell or myeloid lineage). This type of leukaemia is associated with poor prognosis and a poor response to intensive chemotherapy, though this finding is still debated. Our patient displayed an inferior response to induction therapy. The main purpose of this report is to make Belgian physicians aware of this entity and its controversial prognostic significance.
(BELG J HEMATOL 2017;8(2):75–9)
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