Articles

Practical management of newly-diagnosed multiple myeloma: 2018 update for transplant eligible patients

BJH - volume 10, issue 3, may 2019

M.C. Vekemans MD, N. Meuleman MD, PhD, C. Doyen MD, PhD, K.L. Wu MD, PhD, P. Mineur MD, G. Bries MD, PhD, A. Kentos MD, L. Michaux MD, PhD, M. Delforge MD, PhD

With the introduction of immunomodulatory agents and proteasome inhibitors, major improvements have been achieved in the treatment and outcome of multiple myeloma. Different treatment combinations are now in use and newer therapies are being developed. Nevertheless, autologous stem cell transplantation remains the corner stone of therapy for fit, newly-diagnosed multiple myeloma patients. Based on an extensive review of the recent literature, we propose recommendations on myeloma care, to be used by haematologists as a reference for daily practice.

(BELG J HEMATOL 2019;10(3):113–21)

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Practical management of newly-diagnosed multiple myeloma: 2018 update for transplant eligible patients

BJH - volume 9, issue Multiple Myeloma Special Edition, december 2018

M.C. Vekemans MD, N. Meuleman MD, PhD, C. Doyen MD, PhD, K.L. Wu MD, PhD, P. Mineur MD, G. Bries MD, PhD, A. Kentos MD, L. Michaux MD, PhD, M. Delforge MD, PhD

SUMMARY

With the introduction of immunomodulatory agents (IMiDs) and proteasome inhibitors (PIs), major improvements have been achieved in the treatment and outcome of multiple myeloma (MM). Different treatment combinations are now in use and newer therapies are being developed. Nevertheless, autologous stem cell transplantation (ASCT) remains the corner stone of therapy for fit, newly-diagnosed MM patients. Based on an extensive review of the recent literature, we propose recommendations on myeloma care, to be used by haematologists as a reference for daily practice.

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First-line treatment of non-transplant eligible multiple myeloma patients

BJH - volume 9, issue Multiple Myeloma Special Edition, december 2018

C. Doyen MD, PhD, M.C. Vekemans MD

SUMMARY

Multiple Myeloma (MM) is mainly a disease of the elderly. In 2018 bortezomib-melphalan-prednisone (VMP) and lenalidomide-dexamethasone (Rd) are the established standard of care first-line regimens. Before starting therapy, an accurate evaluation of the frailty of patients is needed which allows physicians to individualize the approach for the individual patient.

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Highlights in multiple myeloma

BJH - volume 9, issue 1, february 2018

M.C. Vekemans MD

SUMMARY

With more than 900 abstracts focusing on multiple myeloma (MM), the 2017 annual meeting of the American Society of Hematology (ASH) shows once more the great interest of the myeloma community in identifying new potential targets and developing novel therapeutic strategies for this devastating disease.

(BELG J HEMATOL 2018;9(1):8–11)

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