Articles

P08 RESOLVING DOAC INTERFERENCE ON APTT, PT AND LUPUS ANTICOAGULANT TESTING BY THE USE OF ACTIVATED CARBON

BJH - 2019, issue ?, february 2019

G. Frans , E.j.a. Bailleul , P. Meeus MD

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P50 Resolving DOAC interference on lupus anticoagulant testing: evaluation of DOAC-Stop®

BJH - 2018, issue Abstract Book BHS, february 2018

G. Frans , P. Meeus MD, E. Bailleul

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A-139 COMPARISON OF 4T-SCORE AND LABORATORY TESTS IN THE DIAGNOSIS OF HIT

BJH - volume 8, issue Abstract Book BSTH, february 2017

L. Seaux , P. Meeus MD, E. Bailleul

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A-141 INTERFERENCE OF CRP IN LUPUS ANTICOAGULANS TESTING: IS CRP THE ONLY CAUSE?

BJH - volume 8, issue Abstract Book BSTH, february 2017

L. Seaux , P. Meeus MD, E. Bailleul

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The order of draw: much ado about nothing?

BJH - volume 6, issue Abstract Book BSTH, november 2015

C. Indevuyst , W. Schuermans , E. Bailleul , P. Meeus MD

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Concomitant JAK2 V617F positive essential thrombocytemia and BCR-ABL1 positive chronic myeloid leukaemia masked by imatinib therapy for a gastrointestinal stromal tumour

BJH - volume 3, issue 3, september 2012

E. Del Biondo MD, H. De Raeve MD, PhD, G. Huysmans MD, K. Hendrickx MD, E. Wouters MD, P. Vandenberghe MD, PhD, P. Meeus MD

Summary

The coincidence of a Janus Kinase 2 (JAK2) V617F positive myeloproliferative neoplasm (MPN) and a BCR-ABL1 positive chronic myeloid leukaemia (CML) is rare. We present a patient whose bone marrow and peripheral blood showed typical features of essential thrombocytemia (ET). However, the normalisation of the white blood cell (WBC) count after therapy with imatinib for a gastrointestinal stromal tumour (GIST) suggests that an underlying CML was masked, as witnessed by the very low levels of BCR-ABL1 at the haematological diagnosis. The question remains if this is a case of two separate myeloid malignancies or a secondary event (BCR-ABL1 fusion) in a primary JAK2 V617F + ET.

(BELG J HEMATOL 2012:3:105–107)

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