BJH - volume 5, issue 4, december 2014
M-C. Vekemans MD, K. Beel MD, PhD, J. Caers MD, PhD, N. Meuleman MD, PhD, G. Bries MD, PhD, V. Delrieu MD, H. Demuynck MD, B. De Prijck MD, H. De Samblanx MD, A. Deweweire MD, A. Kentos MD, P. Mineur MD, F. Offner MD, PhD, I. Vande Broek MD, PhD, A. Vande Velde MD, J. Van Droogenbroeck MD, PhD, KL. Wu MD, PhD, C. Doyen MD, PhD, R. Schots MD, PhD, M. Delforge MD, PhD
With the introduction of immunomodulatory drugs and proteasome inhibitors, major improvements have been achieved in the treatment and prognosis of multiple myeloma. Different treatment combinations are now in use and innovative therapies are being developed. This rapidly changing therapeutic landscape calls for an update on the Belgian myeloma guidelines, published in 2010.1 Based on an extensive review of the recent literature, the myeloma study group of the Belgian Hematology Society has revised the consensus recommendations on myeloma care, to be used by haematologists as a reference for daily practice. When applicable, comments with regards to the Belgian reimbursement modalities are included. The full text with appendices can be downloaded from the Belgian Hematology Society website (www.bhs.be) and from the Belgium Journal of Hematology website (www.ariez.com).
(BELG J HEMATOL 2014;5(4):125–36)
Read moreBJH - volume 5, issue Abstract Book BHS, january 2014
F. Trullemans , R. Mertens , M.C. Chintinne , R. Schots MD, PhD
BJH - volume 5, issue Abstract Book BHS, january 2014
K. Fostier MD, J. Corthals , C. Heirman , J.L. Aerts , K. Thielemans , R. Schots MD, PhD, B. De Keersmaecker
BJH - volume 5, issue Abstract Book BHS, january 2014
J. Caers MD, PhD, M-C. Vekemans MD, I. Vande Broek MD, PhD, V. Maertens MD, P.H. Mineur , G. Bries MD, PhD, E. Vandeneste , G. Vanstraelen , K. Beel MD, PhD, F. Leleu , H. Demuynck MD, C. Scheurmans , A. Van de Velde MD, W. Schroyens MD, PhD, K.L. Wu MD, PhD, N. Meuleman MD, PhD, R. Schots MD, PhD, M. Delforge MD, PhD, C. Doyen MD, PhD
BJH - volume 5, issue Abstract Book BHS, january 2014
X. Galloo , C. Caron , L. Pipeleers , K. Wissing , K. Fostier MD, F. Trullemans , C. Tielemans , R. Schots MD, PhD, A. De Becker MD
BJH - volume 5, issue Abstract Book BHS, january 2014
F. Baron MD, PhD, P. Zachée MD, PhD, J. Maertens MD, PhD, T. Kerre MD, PhD, A. Ory , L. Seidel , C. Graux MD, PhD, P. Lewalle MD, PhD, H. Schouten , K. Theunissen , R. Schots MD, PhD, Y. Beguin MD, PhD
BJH - volume 4, issue 1, march 2013
K. Fostier MD, A. De Becker MD, R. Schots MD, PhD
The immunomodulatory drugs (IMiDs) are a class of orally available compounds which are licensed for the treatment of multiple myeloma (thalidomide, lenalidomide) and transfusion-dependent low- and intermediate-risk myelodysplasia (MDS) with deletion of long arm of chromosome 5 (lenalidomide). Pomalidomide, a novel second generation IMiD, is entering clinical trials and seems to further broaden the therapeutic spectrum of these already pleiotropic drugs. Here we summarise new insights into the mechanism of action of IMiDs as well as new developments related to their clinical use, as maintenance therapy in multiple myeloma (MM), in the treatment of myeloproliferative neoplasm- associated myelofibrosis, other types of MDS, chronic lymphocytic leukaemia (CLL) and sickle cell disease (SCD).
(BELG J HEMATOL 2013;1:21–28)
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