BJH - volume 10, issue 2, march 2019
S. Dubruille PhD, V. Thibaud MD, T. Pepersack MD, PhD, D. Bron MD, PhD
Frailty assessment in older patients with malignant hemopathies is very useful in order to improve care and treatment options. However, some lacks of data exist regarding the unsuspected frail population in presumed ‘clinically fit’ patients who should not benefit from chemotherapy. In this article, we review current data regarding prognostic factors and frailty scoring in older patients with malignant hemopathies. Prospective trials are needed to build a new frailty scoring to assess the unsuspected frail population in ‘clinically fit’ patients including specifically assessment of cognitive impairment.
(BELG J HEMATOL 2019;10(2):65–8)
Read moreBJH - 2018, issue Abstract Book BHS, february 2018
S. Dubruille PhD, C. Kenis , Y. Libert PhD, M. Delforge MD, PhD, L. Dal Lago , M. Roos , C. Borghgraef , A. Salaroli , M. Maerevoet MD, D. Razavi MD, PhD, H. Wildiers , D. Bron MD, PhD
BJH - volume 8, issue Abstract Book BHS, february 2017
S. Dubruille PhD, C. Kenis , Y. Libert PhD, M. Delforge MD, PhD, J. Alexis Ruiz , M. Roos , A. Collard , N. Meuleman MD, PhD, M. Maerevoet MD, D. Razavi MD, PhD, H. Wildiers , D. Bron MD, PhD
BJH - volume 7, issue 5, october 2016
S. Dubruille PhD, Y. Libert PhD, D. Razavi MD, PhD, D. Bron MD, PhD
A Comprehensive Geriatric Assessment is recommended to detect vulnerable cancer patients for whom chemotherapy may lead to severe impairment on functionality, quality of life, or survival. Although Comprehensive Geriatric Assessment is useful for better management of older patients with unsuspected problems, little is known about the reliability of the Comprehensive Geriatric Assessment to optimise the therapeutic approach in a specific patient with a malignant haemopathy. Particularly, the prognostic value of cognitive impairment in clinically fit older patients with haematological malignancies admitted to receive chemotherapy, are poorly investigated. This article investigated this question and tries to explain links between cognitive impairment and poor overall survival. Finally, this article tries to propose supportive interventions to reduce morbidity and mortality in older cancer patients with cognitive impairment.
(BELG J HEMATOL 2016;7(5):180–3)
Read moreBJH - volume 7, issue Abstract Book BHS, january 2016
S. Dubruille PhD, Y. Libert PhD, M. Roos , S. Vandenbossche , A. Collard , N. Meuleman MD, PhD, M. Maerevoet MD, A. Etienne , C. Reynaert , D. Razavi MD, PhD, D. Bron MD, PhD
BJH - volume 5, issue Abstract Book BHS, january 2014
S. Dubruille PhD, Y. Libert PhD, M. Roos , S. Vandenbossche , N. Meuleman MD, PhD, M. Maerevoet MD, D. Razavi MD, PhD, D. Bron MD, PhD
BJH - 2013, issue BHS Abstractbook, january 2013
S. Dubruille PhD, M. Maerevoet MD, R. Roos , V. Vandenbossche , N. Meuleman MD, PhD, Y. Libert PhD, D. Bron MD, PhD
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