BJH - volume 11, issue Abstract Book BHS, february 2020
S. Servais MD, PhD, F. Baron MD, PhD, C. Lechanteur PhD, E. Baudoux MD, A. Briquet PhD, D. Selleslag MD, J. Maertens MD, PhD, X. Poiré MD, W. Schroyens MD, PhD, C. Graux MD, PhD, A. De Becker MD, R. Schots MD, PhD, P. Zachée MD, PhD, A. Ory , J. Herman , T. Kerre MD, PhD, Y. Beguin MD, PhD
BJH - volume 10, issue 8, december 2019
T. Feys MBA, MSc, G. Roex , Y. Beguin MD, PhD, T. Kerre MD, PhD, X. Poiré MD, P. Lewalle MD, PhD, P. Vandenberghe MD, PhD, D. Bron MD, PhD, S. Anguille MD, PhD
Chimeric antigen receptor (CAR) T-cell therapy is a new cancer immunotherapy targeting specific cell surface antigens. This type of adoptive cell immunotherapy has been a breakthrough in the treatment of aggressive B-cell lymphoma and B-cell precursor acute lymphoblastic leukaemia (ALL) and is currently also being studied in other cancer types, including multiple myeloma and chronic lymphocytic leukaemia. This review will discuss the recent clinical developments and future perspectives of CAR T-cell therapy, with a focus on the clinical trials that led to the FDA and EMA approval of tisagenlecleucel (Kymriah®, Novartis) and axicabtagene ciloleucel (Yescarta®, Gilead) for the treatment of childhood/adult relapsed/refractory (r/r) B-cell precursor ALL and aggressive B-cell non-Hodgkin lymphoma.
(BELG J HEMATOL 2019;10(8):301–10)
Read moreBJH - 2018, issue Abstract Book BHS, february 2018
F. Van Obbergh MD, N. Vanlangendonck , A. Van Maanen , P. Van Muylder , A. Ferrant , C. Lambert MD, E. Van den Neste MD, PhD, D. Latinne , X. Poiré MD
BJH - 2018, issue Abstract Book BHS, february 2018
S. Dupriez , A. Ferrant , M-C. Vekemans MD, B. Brichard , L. Michaux MD, PhD, T. Connerotte , E. Van den Neste MD, PhD, C. Vermylen , L. Knoops MD, PhD, C. Graux MD, PhD, F. Duhoux , C. Lambert MD, X. Poiré MD, H.A. Poirel MD, PhD
BJH - 2018, issue Abstract Book BHS, february 2018
Y. Berners , A. Capes , F. Dall’Armellina , L. Maindiaux , J. Morelle , K. Claes , C. Lambert MD, X. Poiré MD, M-C. Vekemans MD
BJH - 2018, issue Abstract Book BHS, february 2018
A. Capes , F. Dall’Armellina , Y. Berners , L. Maindiaux , T. Connerotte , A. Camboni MD, PhD, P. Saussoy MD, PhD, J-P. Defour PhD, X. Poiré MD, N. Straetmans MD, PhD, M-C. Vekemans MD
BJH - volume 8, issue Abstract Book BHS, february 2017
X. Poiré MD, C. Graux MD, PhD, A. Ory , J. Jamart , F. Frédéric , H. Schoemans MD, PhD, P. Lewalle MD, PhD, A. De Becker MD, D. Deeren , Z. Berneman MD, PhD, T. Kerre MD, PhD, P. Zachée MD, PhD, D. Selleslag MD, Y. Beguin MD, PhD
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